heat-shock proteins

heat-shock proteins
Families of proteins conserved through pro- and eukaryotic cells, induced in cells as a result of a variety of environmental stresses, though some are constitutively expressed. Some serve to stabilize proteins in abnormal configurations, play a role in folding and unfolding of proteins and the assembly of oligomeric complexes, and may act as chaperonins. Hsp90 complexes with inactive steroid hormone receptor and is displaced upon ligand binding. Four major subclasses are recognized: hsp90, hsp70, hsp60 and small hsps. Hsps have been suggested to act as major immunogens in many infections.

Dictionary of molecular biology. 2004.

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  • heat-shock proteins — heat shock proteins. См. белки теплового шока. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • heat-shock proteins — Proteins produced when cells are exposed to high temperatures or other stressful conditions. They protect the cells from damage and often aid in the proper folding of proteins …   Dictionary of microbiology

  • Small heat shock proteins — Kleine Hitzeschockproteine (engl. small heat shock proteins, kurz sHsps) sind Proteine mit Molekülmassen von 12 bis 42 kDa. Sie gehören zur Familie der Hitzeschockproteine, die bei Hitze und anderen zellulären Stresssituationen vermehrt gebildet… …   Deutsch Wikipedia

  • Heat shock protein — Heat shock proteins (HSP) are a group of proteins whose expression is increased when the cells are exposed to elevated temperatures or other stress. This increase in expression is transcriptionally regulated. This dramatic upregulation of the… …   Wikipedia

  • Heat shock — In biochemistry, heat shock is the effect of subjecting a cell to a higher temperature than that of the ideal body temperature of the organism from which the cell line was derived. Heat shock proteins (HSPs) are a part of the cell s internal… …   Wikipedia

  • Heat shock factor — Pfam box Name = HSF type DNA binding Symbol = HSF DNA bind width = 300px caption = Structure of the dimeric DNA binding domain of the yeast heat shock factor (cyan and green) bound to DNA (brown) based on PDB|3HTS. Pfam= PF00447 InterPro=… …   Wikipedia

  • Heat Shock Protein — Hitzeschockproteine (engl. Heat Shock Protein, HSP) sind Proteine, die anderen Proteinen bei der Faltung oder bei der Erhaltung ihrer Sekundärstruktur unter Extrembedingungen helfen. Sie werden in erhöhtem Maße gebildet, nachdem Zellen Hitze oder …   Deutsch Wikipedia

  • Heat shock protein — Protéine de choc thermique Les protéines de choc thermique ou HSP (pour Heat Shock Proteins), sont une classe de protéines chaperonnes initialement découvertes en raison de leur inductibilité par la chaleur. Leur rôle, crucial pour toutes les… …   Wikipédia en Français

  • heat-shock factor — See heat shock proteins …   Dictionary of molecular biology

  • Heat shock protein 47 — Heat shock protein 47, also known as SERPINH1 is a serpin which serves as a human chaperone protein for collagen.cite web | title = Entrez Gene: SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding… …   Wikipedia

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